嗜睡者請進 - 憂鬱症

講到維他命C缺乏會造成嗜睡
主要原因是維他命C關係到身體內肉鹼(carnitine)的合成
順便補充,肉鹼跟身體細胞能量的產生息息相關

文章內有肉鹼(carnitine)的名詞解釋連結


出處: 奧勒岡州立大學 微營養中心 維他命C
https://lpi.oregonstate.edu/mic/vitamins/vitamin-C

以下是

原文和翻譯 我直接用google翻譯翻 翻不好請去怪google 別怪我 XDDDDD

我是覺得翻得很順 google翻譯真是強大

The role of vitamin C as a cofactor is also related to its redox potential.
By maintaining enzyme-bound metals in their reduced forms, vitamin C assists
mixed-function oxidases in the synthesis of several critical biomolecules (1).
These enzymes are either monooxygenases or dioxygenases (see Table 1).
Symptoms of vitamin C deficiency, such as poor wound healing and lethargy,
likely result from the impairment of these vitamin C-dependent enzymatic
reactions leading to the insufficient synthesis of
collagen, carnitine, and catecholamines (see Deficiency). Moreover,
several dioxygenases involved in the regulation of gene expression and
the maintenance of genome integrity require vitamin C as a cofactor.
Indeed, research has recently uncovered the crucial role played by enzymes,
such as the TET dioxygenases and Jumonji domain-containing histone
demethylases, in the fate of cells and tissues (see Table 1). These enzymes
contribute to the epigenetic regulation of gene expression by catalyzing
reactions involved in the demethylation of DNA and histones.

維生素C作為輔助因子的作用也與其氧化還原電位有關。通過維持還原形式

的酶結合金屬，維生素C有助於合成幾種關鍵生物分子中的混合功能氧化酶（1）。

這些酉每是單加氧酶或雙加氧酶（見表1）。

維生素C缺乏的症狀，例如傷口癒合不良和嗜睡，

可能是由於這些維生素C依賴性酶促反應的損害導致膠原蛋白，肉鹼和兒茶酚胺的合成不足

（見缺乏症）。此外，參與調節基因表達和維持基因組完整性的幾種雙加氧酶需要維生素

C作為輔助因子。實際上，研究最近揭示了酶在細胞和組織的命運中發揮的關鍵作用，

例如TET雙加氧酶和含有組蛋白去甲基化酶的Jumonji結構域（參見表1）。這些

酶通過催化參與DNA和組蛋白去甲基化的反應而促成基因表達的表觀遺傳調節。


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