為什麼冷會感冒？ - 醫療資訊,議題討論

※ 引述《Copper (　　　　　　　　　　　)》之銘言：
: ※ 引述《alcoholic (December)》之銘言：
: : 不不不
: : 這是有科學根據的
: : 根據我去年唸微免的一點點印象
: 這不叫科學根據..:)
: : 睡覺的時候
: : 冷跟感冒的確有關係喔
: 是, 這是相關性, 但先前的討論是指"因果性"--冷是否會讓人更容易感染感冒病毒?
: (host factor)
: 透過實驗的設計, 可以很容易去除冷和病毒的雙變項....
: 至今, 仍無證據能支持....
: : rhinovirus只適合在攝氏33度
: : 若平時身體習慣於溫暖空氣的人
: : 暴露在較冷的空氣中
: : 組織可能沒有將上呼吸道的血流增加到足以維持33度以上
: : 就會得感冒了
: 這是推理, 但得不到實證
: : 所以晚上睡覺滾出棉被而不自知 就很容易感冒囉
有空麻煩參考一下下列論文
其中有的事實驗 也有review
Low temperature and pressure stability of picornaviruses: Implications for
virus uncoating.
Andrea C Oliveira, Daniella Ishimaru, Rafael B Goncalves,
Thomas J Smith, et al. Biophysical Journal. New York: Mar 1999. Vol. 76, Iss.
3; p. 1270

Acute viral infections of upper respiratory tract in elderly people living in
the
community: Comparative, prospective, population based study of disease burden.
Karl G Nicholson, Julie Kent, Victoria Hammersley, Esperanza Cancio.
British Medical Journal (International edition). London: Oct 25, 1997. Vol. 315,
Iss. 7115; p. 1060

Risk factors for lower respiratory complications of rhinovirus infections in
elderly people living in the community: Prospective cohort study.
Nicholson, Karl G, Kent, Julie, Hammersley, Victoria, Cancio, Esperanza.
British Medical Journal (International edition). London: Nov 2, 1996. Vol. 313,
Iss. 7065; p. 1119

Effect of inhaling heated vapor on symptoms of the common cold.
Forstall, Gregory J, Macknin, Michael L, Yen-Lieberman, Belinda R, Medendorp,
Sharon VanderBrug. JAMA. Chicago: Apr 13, 1994. Vol. 271, Iss. 14; p. 1109


Clarithromycin on Experimental Rhinovirus-16 Colds:
A Randomized, Double-Blind, Controlled Trial.
Abisheganaden, John A. MBBS. Avila, Pedro C. MD. Kishiyama, Jeffrey L. MD. Liu,
Jane MS. Yagi, Shigeo MS. Schnurr, David PhD. Boushey, Homer A. MD. Effect of
American Journal of Medicine. 108(6):453-459, April 15, 2000.


The common cold: Cold water on hot news
Monto, Arnold S. JAMA. Chicago: Apr 13, 1994. Vol. 271, Iss. 14; p. 1122


Human major group rhinoviruses downmodulate the accessory function of monocytes
by inducing IL-10.
Stockl, Johannes 1. Vetr, Helga 2. Majdic, Otto 1. Zlabinger, Gerhard 1.
Kuechler, Ernst 2. Knapp, Walter 1. Journal of Clinical Investigation.
104(7):957-965, October 1999.


Mechanism of Rhinovirus-induced Changes in Airway Smooth Muscle Responsiveness.
Hakonarson, Hakon. Maskeri, Neil. Carter, Carrie. Hodinka, Richard L.. Campbell,
Donald. Grunstein, Michael M.. Journal of Clinical Investigation.
102(9):1732-1741, November 1, 1998.


Efficacy and Safety of the Neuraminidase Inhibitor Zanamivir in the Treatment
of Influenzavirus Infections.

Hayden, Frederick G.. Osterhaus, Albert D.M.E.. Treanor, John J.. Fleming,
Douglas M.. Aoki, Fred Y.. Nicholson, Karl G.. Bohnen, Arthur M.. Hirst,
Hilary M.. Keene, Oliver. Wightman, Kevin. New England Journal of Medicine.
337(13):874-880, September 25, 1997.


Risk factors for lower respiratory complications of rhinovirus infections
in elderly people living in the community: prospective cohort study.
Nicholson, Karl G.. Kent, Julie. Hammersley, Victoria. Cancio, Esperanza.
BMJ. 313(7065):1119-1123, November 2, 1996.

Rhinovirus Stimulation of Interleukin-6 In Vivo and In Vitro: Evidence for
Nuclear Factor kappa B-dependent Transcriptional Activation.
Zhu, Zhou ***. Tang, Weiliang *. Ray, Anuradha *. Wu, Yang ***. Einarsson,
Oskar ***. Landry, Marie L. *****. Gwaltney, Jr. Jack****. Elias, Jack A. ***.
Journal of Clinical Investigation. 97(2):421-430, January 15, 1996.

The Common Cold: The Effect of Hot Humid Air on the Nasal Mucosa.
Monto, Arnold S. MD. JAMA. 272(14):1103-1104, October 12, 1994.

Effect of Inhalation of Hot Humidified Air on Experimental Rhinovirus Infection
.Hendley, J. Owen MD. Abbott, Robert D. PhD. Beasley, Patsy P. RN. Gwaltney,
Jack M. Jr, MD. JAMA. 271(14):1112-1113, April 13, 1994.

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