全球首創!清大原子爐以中子光束消除腫瘤 - 化療
By Hedda
at 2016-10-06T22:30
at 2016-10-06T22:30
Table of Contents
※ [本文轉錄自 Gossiping 看板 #1NzW0Cqs ]
作者: ceaserman (神采飛揚) 看板: Gossiping
標題: [新聞] 全球首創!清大原子爐以中子光束消除腫瘤
時間: Thu Oct 6 15:40:56 2016
1.媒體來源:
聯合
2.完整新聞標題:
全球首創!清大原子爐以中子光束消除腫瘤
3.完整新聞內文:
2016-10-05 11:12 聯合報 記者鄭語謙╱即時報導
發展武器或是核能的原子爐,現在則是治療癌症的幫手。傳統癌症化療、開刀至少需要35
次療程,且造成無論好壞器官組織都被破壞,清華大學核子工程語科學教授周鳳英研究團
隊則投入硼中子捕獲治療及研究,利用原子反應爐光束照射,只要2次即可成功消除腫瘤
,且不影響正常細胞功能,在台灣已有超過17個成功的臨床案例,以腦頸部腫瘤治癒居多
,最快半年團隊將展開肝癌的治療的人體臨床實驗。
清大原科中心有一台灣唯一做為研究用的池原子反應爐清水,透過反應爐進行硼中子捕獲
治療,(稱BNCT放射治療),從20幾年開始就與榮總及陽明和日本等醫院、大學合作,成為
全球首創以硼中子捕獲治療癌症,研究成果已發表於國際期刊。
周鳳英表示,硼中子捕獲治療是一種體內標靶輻射治療方式,硼藥物易與腫瘤結合,先
為病患注射含硼藥物後,硼中子會「選擇性」只聚積在腫瘤部位,再用清大原子反應爐
的中子束照射30分鐘,可以有效殺死腫瘤細胞,約2次療程即可成功消除腫瘤,並且不影
響正常肝細胞功能,也沒有明顯副作用。
因硼中子只會蓄積在腫瘤處,對於瀰漫性或是多發性癌症的治療效果特別好,周鳳英說,
過去化療照射所有部位,無論好壞細胞通通被殺死,而硼就像導航員,可讓中子束只殺死
癌細胞,「癌細胞藏到哪就可以追到哪」。
台灣已有17例成功採用硼中子捕獲治癒頭頸癌(包含顏面、鼻咽腔、鼻腔、口腔、咽喉及
頸部的惡性腫瘤))的案例,一名51歲的公務員,先前患有左耳下腺惡性腫瘤,經手術治療
不幸復發且沿顱底侵犯到顱內,經過BNCT放射治療後,不僅腫瘤明顯消失,患者也在3年
前回到工作岡位。
現在團隊將目標轉到國人十大癌症排行總在前三名的「肝癌」治療,周鳳英表示,原本用
於頭頸癌患者所使用的含硼藥物BPA積聚於肝腫瘤效果不明顯,反而可能積聚在鄰近肝臟
的胰臟,不適用於肝癌治療,多方嘗試後,意外發展出可選擇性積聚於肝腫瘤的含硼藥
物-硼酸(BA)。目前已經小動物實驗成功,最快半年後就可以運用在人體臨床實驗。
清大表示,未來,望能將BNCT治療技術轉化成可移動的加速器放在醫院裡,讓病患可以就
近到醫院治療,不用拖著病體舟車勞頓到清華原子爐,但預估此目標需10億元資金才能推
動,「這是使命,我們會持續努力達成。」周鳳英說。
4.完整新聞連結 (或短網址):
http://udn.com/news/story/9/2003725
5.備註:
很訝異這麼重大的醫學發展居然很少人關心。
未來之福阿!
--
--
作者: ceaserman (神采飛揚) 看板: Gossiping
標題: [新聞] 全球首創!清大原子爐以中子光束消除腫瘤
時間: Thu Oct 6 15:40:56 2016
1.媒體來源:
聯合
2.完整新聞標題:
全球首創!清大原子爐以中子光束消除腫瘤
3.完整新聞內文:
2016-10-05 11:12 聯合報 記者鄭語謙╱即時報導
發展武器或是核能的原子爐,現在則是治療癌症的幫手。傳統癌症化療、開刀至少需要35
次療程,且造成無論好壞器官組織都被破壞,清華大學核子工程語科學教授周鳳英研究團
隊則投入硼中子捕獲治療及研究,利用原子反應爐光束照射,只要2次即可成功消除腫瘤
,且不影響正常細胞功能,在台灣已有超過17個成功的臨床案例,以腦頸部腫瘤治癒居多
,最快半年團隊將展開肝癌的治療的人體臨床實驗。
清大原科中心有一台灣唯一做為研究用的池原子反應爐清水,透過反應爐進行硼中子捕獲
治療,(稱BNCT放射治療),從20幾年開始就與榮總及陽明和日本等醫院、大學合作,成為
全球首創以硼中子捕獲治療癌症,研究成果已發表於國際期刊。
周鳳英表示,硼中子捕獲治療是一種體內標靶輻射治療方式,硼藥物易與腫瘤結合,先
為病患注射含硼藥物後,硼中子會「選擇性」只聚積在腫瘤部位,再用清大原子反應爐
的中子束照射30分鐘,可以有效殺死腫瘤細胞,約2次療程即可成功消除腫瘤,並且不影
響正常肝細胞功能,也沒有明顯副作用。
因硼中子只會蓄積在腫瘤處,對於瀰漫性或是多發性癌症的治療效果特別好,周鳳英說,
過去化療照射所有部位,無論好壞細胞通通被殺死,而硼就像導航員,可讓中子束只殺死
癌細胞,「癌細胞藏到哪就可以追到哪」。
台灣已有17例成功採用硼中子捕獲治癒頭頸癌(包含顏面、鼻咽腔、鼻腔、口腔、咽喉及
頸部的惡性腫瘤))的案例,一名51歲的公務員,先前患有左耳下腺惡性腫瘤,經手術治療
不幸復發且沿顱底侵犯到顱內,經過BNCT放射治療後,不僅腫瘤明顯消失,患者也在3年
前回到工作岡位。
現在團隊將目標轉到國人十大癌症排行總在前三名的「肝癌」治療,周鳳英表示,原本用
於頭頸癌患者所使用的含硼藥物BPA積聚於肝腫瘤效果不明顯,反而可能積聚在鄰近肝臟
的胰臟,不適用於肝癌治療,多方嘗試後,意外發展出可選擇性積聚於肝腫瘤的含硼藥
物-硼酸(BA)。目前已經小動物實驗成功,最快半年後就可以運用在人體臨床實驗。
清大表示,未來,望能將BNCT治療技術轉化成可移動的加速器放在醫院裡,讓病患可以就
近到醫院治療,不用拖著病體舟車勞頓到清華原子爐,但預估此目標需10億元資金才能推
動,「這是使命,我們會持續努力達成。」周鳳英說。
4.完整新聞連結 (或短網址):
http://udn.com/news/story/9/2003725
5.備註:
很訝異這麼重大的醫學發展居然很少人關心。
未來之福阿!
--
--
Tags:
化療
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at 2017-10-28T13:16
By Kyle
at 2017-10-30T00:28
at 2017-10-30T00:28
By Eden
at 2017-11-03T02:46
at 2017-11-03T02:46
By Sarah
at 2017-11-06T08:05
at 2017-11-06T08:05
By Olivia
at 2017-11-09T02:38
at 2017-11-09T02:38
By Eden
at 2017-11-13T04:11
at 2017-11-13T04:11
By Iris
at 2017-11-17T09:53
at 2017-11-17T09:53
By Hazel
at 2017-11-19T11:47
at 2017-11-19T11:47
By Eden
at 2017-11-19T18:47
at 2017-11-19T18:47
By Delia
at 2017-11-24T17:50
at 2017-11-24T17:50
By Agnes
at 2017-11-28T14:19
at 2017-11-28T14:19
By Edwina
at 2017-11-30T18:42
at 2017-11-30T18:42
By Jacob
at 2017-12-05T03:59
at 2017-12-05T03:59
By James
at 2017-12-07T03:19
at 2017-12-07T03:19
By Linda
at 2017-12-08T13:09
at 2017-12-08T13:09
By Victoria
at 2017-12-09T01:04
at 2017-12-09T01:04
By Olga
at 2017-12-12T06:34
at 2017-12-12T06:34
By Ina
at 2017-12-12T11:33
at 2017-12-12T11:33
By Ula
at 2017-12-16T17:10
at 2017-12-16T17:10
By Caroline
at 2017-12-17T20:17
at 2017-12-17T20:17
By Adele
at 2017-12-18T12:23
at 2017-12-18T12:23
By Ophelia
at 2017-12-23T01:53
at 2017-12-23T01:53
By Jessica
at 2017-12-24T02:30
at 2017-12-24T02:30
By Dinah
at 2017-12-24T23:04
at 2017-12-24T23:04
By Valerie
at 2017-12-26T12:39
at 2017-12-26T12:39
By Enid
at 2017-12-27T16:38
at 2017-12-27T16:38
By Mia
at 2018-01-01T09:12
at 2018-01-01T09:12
By Isla
at 2018-01-01T23:03
at 2018-01-01T23:03
By Bennie
at 2018-01-02T18:54
at 2018-01-02T18:54
By Yedda
at 2018-01-07T00:45
at 2018-01-07T00:45
By Olivia
at 2018-01-10T12:13
at 2018-01-10T12:13
By Enid
at 2018-01-11T05:25
at 2018-01-11T05:25
By Susan
at 2018-01-13T17:32
at 2018-01-13T17:32
By Belly
at 2018-01-18T01:55
at 2018-01-18T01:55
By Elvira
at 2018-01-19T15:09
at 2018-01-19T15:09
By Linda
at 2018-01-20T19:05
at 2018-01-20T19:05
By George
at 2018-01-23T01:16
at 2018-01-23T01:16
By George
at 2018-01-23T20:17
at 2018-01-23T20:17
By Hedda
at 2018-01-27T04:23
at 2018-01-27T04:23
By Michael
at 2018-01-30T04:34
at 2018-01-30T04:34
By Donna
at 2018-02-02T21:21
at 2018-02-02T21:21
By Donna
at 2018-02-03T23:30
at 2018-02-03T23:30
By Skylar Davis
at 2018-02-06T22:08
at 2018-02-06T22:08
By Lydia
at 2018-02-07T06:10
at 2018-02-07T06:10
By George
at 2018-02-12T00:28
at 2018-02-12T00:28
By Kristin
at 2018-02-13T21:01
at 2018-02-13T21:01
By Erin
at 2018-02-16T05:51
at 2018-02-16T05:51
By Yuri
at 2018-02-16T21:18
at 2018-02-16T21:18
By Brianna
at 2018-02-19T06:41
at 2018-02-19T06:41
By Hedy
at 2018-02-21T01:04
at 2018-02-21T01:04
By Joseph
at 2018-02-25T08:10
at 2018-02-25T08:10
By Tristan Cohan
at 2018-02-27T18:24
at 2018-02-27T18:24
By Hedwig
at 2018-02-27T20:51
at 2018-02-27T20:51
By Ethan
at 2018-03-01T08:23
at 2018-03-01T08:23
By Delia
at 2018-03-03T21:04
at 2018-03-03T21:04
By Elizabeth
at 2018-03-06T19:25
at 2018-03-06T19:25
By Hedy
at 2018-03-07T06:47
at 2018-03-07T06:47
By Eden
at 2018-03-09T04:28
at 2018-03-09T04:28
By Audriana
at 2018-03-12T10:28
at 2018-03-12T10:28
By Ivy
at 2018-03-16T10:32
at 2018-03-16T10:32
By Steve
at 2018-03-18T12:51
at 2018-03-18T12:51
By Daniel
at 2018-03-21T20:48
at 2018-03-21T20:48
By Kama
at 2018-03-25T21:16
at 2018-03-25T21:16
By Poppy
at 2018-03-26T14:38
at 2018-03-26T14:38
By Hedda
at 2018-03-26T17:34
at 2018-03-26T17:34
By Carolina Franco
at 2018-03-27T13:11
at 2018-03-27T13:11
By Anthony
at 2018-03-29T04:00
at 2018-03-29T04:00
By Erin
at 2018-04-02T22:04
at 2018-04-02T22:04
By Barb Cronin
at 2018-04-03T23:11
at 2018-04-03T23:11
By Oliver
at 2018-04-08T05:43
at 2018-04-08T05:43
By Callum
at 2018-04-08T19:44
at 2018-04-08T19:44
By Frederic
at 2018-04-09T00:46
at 2018-04-09T00:46
By Valerie
at 2018-04-12T17:04
at 2018-04-12T17:04
By Belly
at 2018-04-15T16:35
at 2018-04-15T16:35
By Donna
at 2018-04-16T06:54
at 2018-04-16T06:54
By Faithe
at 2018-04-18T11:41
at 2018-04-18T11:41
By Ivy
at 2018-04-23T10:33
at 2018-04-23T10:33
By Puput
at 2018-04-25T11:40
at 2018-04-25T11:40
By Lucy
at 2018-04-27T07:52
at 2018-04-27T07:52
By Gary
at 2018-04-27T22:27
at 2018-04-27T22:27
By Xanthe
at 2018-04-28T08:24
at 2018-04-28T08:24
By Emma
at 2018-04-30T09:23
at 2018-04-30T09:23
By Frederic
at 2018-05-01T08:10
at 2018-05-01T08:10
By Elvira
at 2018-05-03T21:20
at 2018-05-03T21:20
By George
at 2018-05-06T06:00
at 2018-05-06T06:00
By Zanna
at 2018-05-09T07:16
at 2018-05-09T07:16
By Ina
at 2018-05-10T09:43
at 2018-05-10T09:43
By Bennie
at 2018-05-10T16:24
at 2018-05-10T16:24
By David
at 2018-05-12T07:21
at 2018-05-12T07:21
By Kama
at 2018-05-14T20:02
at 2018-05-14T20:02
By Mia
at 2018-05-16T12:11
at 2018-05-16T12:11
By Brianna
at 2018-05-19T01:03
at 2018-05-19T01:03
By Necoo
at 2018-05-23T00:07
at 2018-05-23T00:07
By Anonymous
at 2018-05-24T08:50
at 2018-05-24T08:50
By David
at 2018-05-27T01:50
at 2018-05-27T01:50
By Dorothy
at 2018-05-27T05:24
at 2018-05-27T05:24
By Leila
at 2018-05-27T09:00
at 2018-05-27T09:00
By Sarah
at 2018-05-28T11:21
at 2018-05-28T11:21
By Megan
at 2018-05-31T23:24
at 2018-05-31T23:24
By Emily
at 2018-06-05T17:10
at 2018-06-05T17:10
By Zora
at 2018-06-09T06:55
at 2018-06-09T06:55
By Hazel
at 2018-06-13T18:29
at 2018-06-13T18:29
By Erin
at 2018-06-16T16:16
at 2018-06-16T16:16
By Bennie
at 2018-06-18T12:55
at 2018-06-18T12:55
By Jessica
at 2018-06-18T21:29
at 2018-06-18T21:29
By Tristan Cohan
at 2018-06-20T15:23
at 2018-06-20T15:23
By Leila
at 2018-06-25T06:04
at 2018-06-25T06:04
By Christine
at 2018-06-25T07:24
at 2018-06-25T07:24
By Eartha
at 2018-06-28T20:36
at 2018-06-28T20:36
By Heather
at 2018-07-03T18:41
at 2018-07-03T18:41
By Zora
at 2018-07-04T18:42
at 2018-07-04T18:42
By Barb Cronin
at 2018-07-07T05:44
at 2018-07-07T05:44
By Edwina
at 2018-07-12T02:20
at 2018-07-12T02:20
By Frederic
at 2018-07-15T07:03
at 2018-07-15T07:03
By Annie
at 2018-07-19T03:14
at 2018-07-19T03:14
By Franklin
at 2018-07-23T06:28
at 2018-07-23T06:28
By Valerie
at 2018-07-26T01:54
at 2018-07-26T01:54
By Donna
at 2018-07-28T01:08
at 2018-07-28T01:08
By Lily
at 2018-07-31T05:05
at 2018-07-31T05:05
By Ethan
at 2018-08-02T08:33
at 2018-08-02T08:33
By Margaret
at 2018-08-03T04:34
at 2018-08-03T04:34
By Jacob
at 2018-08-05T05:51
at 2018-08-05T05:51
By Belly
at 2018-08-08T13:37
at 2018-08-08T13:37
By Jacob
at 2018-08-09T20:28
at 2018-08-09T20:28
By Ethan
at 2018-08-13T08:09
at 2018-08-13T08:09
By Lydia
at 2018-08-17T05:42
at 2018-08-17T05:42
By Regina
at 2018-08-18T00:12
at 2018-08-18T00:12
By Tristan Cohan
at 2018-08-20T14:29
at 2018-08-20T14:29
By Caroline
at 2018-08-25T14:24
at 2018-08-25T14:24
By Donna
at 2018-08-27T05:56
at 2018-08-27T05:56
By Frederic
at 2018-09-01T04:35
at 2018-09-01T04:35
By William
at 2018-09-02T04:47
at 2018-09-02T04:47
By Andy
at 2018-09-05T12:58
at 2018-09-05T12:58
By Sierra Rose
at 2018-09-07T10:09
at 2018-09-07T10:09
By Ophelia
at 2018-09-09T04:55
at 2018-09-09T04:55
By George
at 2018-09-11T22:58
at 2018-09-11T22:58
By Anonymous
at 2018-09-13T06:05
at 2018-09-13T06:05
By George
at 2018-09-15T15:21
at 2018-09-15T15:21
By Lauren
at 2018-09-20T01:32
at 2018-09-20T01:32
By Tom
at 2018-09-24T05:15
at 2018-09-24T05:15
By Joe
at 2018-09-27T19:34
at 2018-09-27T19:34
By Todd Johnson
at 2018-09-29T12:41
at 2018-09-29T12:41
By Catherine
at 2018-09-30T04:17
at 2018-09-30T04:17
By Tristan Cohan
at 2018-09-30T16:20
at 2018-09-30T16:20
By Hedy
at 2018-10-02T12:15
at 2018-10-02T12:15
By Hedy
at 2018-10-03T14:15
at 2018-10-03T14:15
By Lydia
at 2018-10-08T08:16
at 2018-10-08T08:16
By Rebecca
at 2018-10-09T12:57
at 2018-10-09T12:57
By Dorothy
at 2018-10-13T03:43
at 2018-10-13T03:43
By Erin
at 2018-10-18T01:09
at 2018-10-18T01:09
By Kelly
at 2018-10-19T07:02
at 2018-10-19T07:02
By Rachel
at 2018-10-21T01:48
at 2018-10-21T01:48
By Ula
at 2018-10-23T00:23
at 2018-10-23T00:23
By Carolina Franco
at 2018-10-26T00:54
at 2018-10-26T00:54
By Agatha
at 2018-10-30T05:20
at 2018-10-30T05:20
By Connor
at 2018-10-31T14:29
at 2018-10-31T14:29
By Quintina
at 2018-11-04T11:59
at 2018-11-04T11:59
By Carolina Franco
at 2018-11-06T11:39
at 2018-11-06T11:39
By Isla
at 2018-11-07T00:02
at 2018-11-07T00:02
By John
at 2018-11-08T20:08
at 2018-11-08T20:08
By Mason
at 2018-11-11T00:04
at 2018-11-11T00:04
By Tom
at 2018-11-14T10:51
at 2018-11-14T10:51
By Frederic
at 2018-11-18T01:24
at 2018-11-18T01:24
By Audriana
at 2018-11-19T08:27
at 2018-11-19T08:27
By John
at 2018-11-21T08:38
at 2018-11-21T08:38
By Doris
at 2018-11-23T07:57
at 2018-11-23T07:57
By Ethan
at 2018-11-23T17:59
at 2018-11-23T17:59
By Doris
at 2018-11-23T23:58
at 2018-11-23T23:58
By Lily
at 2018-11-24T11:40
at 2018-11-24T11:40
By Anthony
at 2018-11-28T14:14
at 2018-11-28T14:14
By Lydia
at 2018-11-28T15:27
at 2018-11-28T15:27
By Hedy
at 2018-11-30T12:10
at 2018-11-30T12:10
By Delia
at 2018-11-30T18:48
at 2018-11-30T18:48
By Edward Lewis
at 2018-12-02T12:02
at 2018-12-02T12:02
By Edward Lewis
at 2018-12-06T22:40
at 2018-12-06T22:40
By Steve
at 2018-12-09T07:59
at 2018-12-09T07:59
By Kama
at 2018-12-11T06:48
at 2018-12-11T06:48
By Faithe
at 2018-12-14T02:05
at 2018-12-14T02:05
By Skylar Davis
at 2018-12-16T14:56
at 2018-12-16T14:56
By Rae
at 2018-12-18T02:52
at 2018-12-18T02:52
By Elvira
at 2018-12-21T19:46
at 2018-12-21T19:46
By Necoo
at 2018-12-22T20:16
at 2018-12-22T20:16
By Regina
at 2018-12-27T04:07
at 2018-12-27T04:07
By Michael
at 2018-12-27T07:06
at 2018-12-27T07:06
By Callum
at 2018-12-31T11:27
at 2018-12-31T11:27
By Daph Bay
at 2019-01-04T15:11
at 2019-01-04T15:11
By Annie
at 2019-01-05T08:21
at 2019-01-05T08:21
By Michael
at 2019-01-08T18:04
at 2019-01-08T18:04
By Harry
at 2019-01-08T22:20
at 2019-01-08T22:20
By Skylar DavisLinda
at 2019-01-13T07:48
at 2019-01-13T07:48
By Odelette
at 2019-01-17T18:22
at 2019-01-17T18:22
By Elizabeth
at 2019-01-20T14:55
at 2019-01-20T14:55
By Ursula
at 2019-01-20T17:13
at 2019-01-20T17:13
By Jacky
at 2019-01-24T17:17
at 2019-01-24T17:17
By Charlotte
at 2019-01-26T02:51
at 2019-01-26T02:51
By Ursula
at 2019-01-26T09:48
at 2019-01-26T09:48
By Queena
at 2019-01-30T05:59
at 2019-01-30T05:59
By Todd Johnson
at 2019-02-02T12:46
at 2019-02-02T12:46
By Belly
at 2019-02-07T00:17
at 2019-02-07T00:17
By Wallis
at 2019-02-07T15:57
at 2019-02-07T15:57
By James
at 2019-02-09T10:20
at 2019-02-09T10:20
By Sierra Rose
at 2019-02-13T08:42
at 2019-02-13T08:42
By Bethany
at 2019-02-13T10:20
at 2019-02-13T10:20
By Ingrid
at 2019-02-16T00:03
at 2019-02-16T00:03
By Michael
at 2019-02-17T10:49
at 2019-02-17T10:49
By Madame
at 2019-02-21T21:49
at 2019-02-21T21:49
By Caitlin
at 2019-02-25T05:51
at 2019-02-25T05:51
By Eartha
at 2019-03-01T01:28
at 2019-03-01T01:28
By Quanna
at 2019-03-05T02:16
at 2019-03-05T02:16
By Valerie
at 2019-03-08T21:03
at 2019-03-08T21:03
By Quanna
at 2019-03-11T00:53
at 2019-03-11T00:53
By Lydia
at 2019-03-12T01:12
at 2019-03-12T01:12
By Quanna
at 2019-03-15T20:08
at 2019-03-15T20:08
By Dinah
at 2019-03-19T10:26
at 2019-03-19T10:26
By Dora
at 2019-03-20T04:24
at 2019-03-20T04:24
By Susan
at 2019-03-23T18:44
at 2019-03-23T18:44
By Carolina Franco
at 2019-03-25T18:16
at 2019-03-25T18:16
By Skylar Davis
at 2019-03-29T21:47
at 2019-03-29T21:47
By Susan
at 2019-03-31T09:00
at 2019-03-31T09:00
By Kristin
at 2019-04-02T00:27
at 2019-04-02T00:27
By Ivy
at 2019-04-06T00:53
at 2019-04-06T00:53
By Eden
at 2019-04-10T22:08
at 2019-04-10T22:08
By Todd Johnson
at 2019-04-15T08:27
at 2019-04-15T08:27
By Elma
at 2019-04-16T18:23
at 2019-04-16T18:23
By Hedda
at 2019-04-17T00:31
at 2019-04-17T00:31
By Regina
at 2019-04-19T10:56
at 2019-04-19T10:56
By Dora
at 2019-04-19T14:13
at 2019-04-19T14:13
By Linda
at 2019-04-22T15:15
at 2019-04-22T15:15
By Michael
at 2019-04-25T04:34
at 2019-04-25T04:34
By Michael
at 2019-04-29T09:24
at 2019-04-29T09:24
By Bethany
at 2019-05-01T15:44
at 2019-05-01T15:44
By Dorothy
at 2019-05-03T09:57
at 2019-05-03T09:57
By David
at 2019-05-07T20:23
at 2019-05-07T20:23
By Skylar DavisLinda
at 2019-05-11T20:26
at 2019-05-11T20:26
By Freda
at 2019-05-12T02:29
at 2019-05-12T02:29
By Joseph
at 2019-05-13T08:10
at 2019-05-13T08:10
By Joe
at 2019-05-13T22:42
at 2019-05-13T22:42
By Caitlin
at 2019-05-14T00:13
at 2019-05-14T00:13
By Erin
at 2019-05-15T06:05
at 2019-05-15T06:05
By Tom
at 2019-05-19T16:00
at 2019-05-19T16:00
By Lucy
at 2019-05-22T11:13
at 2019-05-22T11:13
By Zenobia
at 2019-05-26T23:59
at 2019-05-26T23:59
By Ursula
at 2019-05-30T01:34
at 2019-05-30T01:34
By Christine
at 2019-05-30T10:51
at 2019-05-30T10:51
By Jacky
at 2019-06-04T04:54
at 2019-06-04T04:54
By Xanthe
at 2019-06-08T14:20
at 2019-06-08T14:20
By Audriana
at 2019-06-09T08:09
at 2019-06-09T08:09
By Sarah
at 2019-06-11T12:20
at 2019-06-11T12:20
By Frederica
at 2019-06-14T01:29
at 2019-06-14T01:29
By Ina
at 2019-06-18T05:27
at 2019-06-18T05:27
By Anonymous
at 2019-06-20T22:08
at 2019-06-20T22:08
By Olga
at 2019-06-25T20:41
at 2019-06-25T20:41
By Edwina
at 2019-06-27T13:11
at 2019-06-27T13:11
By Isabella
at 2019-07-01T08:43
at 2019-07-01T08:43
By Madame
at 2019-07-02T08:35
at 2019-07-02T08:35
By Daph Bay
at 2019-07-02T22:51
at 2019-07-02T22:51
By Tristan Cohan
at 2019-07-04T16:36
at 2019-07-04T16:36
By Joseph
at 2019-07-08T00:17
at 2019-07-08T00:17
By David
at 2019-07-09T03:16
at 2019-07-09T03:16
By Callum
at 2019-07-12T18:12
at 2019-07-12T18:12
By Valerie
at 2019-07-17T15:28
at 2019-07-17T15:28
By Isla
at 2019-07-20T20:52
at 2019-07-20T20:52
By Thomas
at 2019-07-25T14:54
at 2019-07-25T14:54
By Gilbert
at 2019-07-29T14:57
at 2019-07-29T14:57
By Barb Cronin
at 2019-08-02T22:40
at 2019-08-02T22:40
By Dora
at 2019-08-04T00:36
at 2019-08-04T00:36
By Gary
at 2019-08-06T12:27
at 2019-08-06T12:27
By Enid
at 2019-08-09T02:43
at 2019-08-09T02:43
By Sierra Rose
at 2019-08-10T15:25
at 2019-08-10T15:25
By Olive
at 2019-08-12T00:45
at 2019-08-12T00:45
By Genevieve
at 2019-08-13T17:30
at 2019-08-13T17:30
By Xanthe
at 2019-08-16T07:10
at 2019-08-16T07:10
By Gary
at 2019-08-19T17:28
at 2019-08-19T17:28
By Catherine
at 2019-08-24T17:27
at 2019-08-24T17:27
By Zanna
at 2019-08-26T18:43
at 2019-08-26T18:43
By Anonymous
at 2019-08-31T05:14
at 2019-08-31T05:14
By Zora
at 2019-09-02T03:38
at 2019-09-02T03:38
By Annie
at 2019-09-06T04:08
at 2019-09-06T04:08
By Isabella
at 2019-09-09T05:21
at 2019-09-09T05:21
By Quintina
at 2019-09-13T21:17
at 2019-09-13T21:17
By Puput
at 2019-09-14T00:29
at 2019-09-14T00:29
By Kumar
at 2019-09-16T09:42
at 2019-09-16T09:42
By Kyle
at 2019-09-18T14:31
at 2019-09-18T14:31
By Suhail Hany
at 2019-09-20T00:09
at 2019-09-20T00:09
By Gilbert
at 2019-09-23T09:47
at 2019-09-23T09:47
By Freda
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at 2019-09-29T17:06
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at 2019-10-07T03:30
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at 2019-10-31T10:22
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at 2019-11-04T23:06
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at 2019-11-06T09:04
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at 2019-11-08T16:17
at 2019-11-08T16:17
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at 2019-11-09T01:40
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at 2019-11-13T08:35
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at 2019-11-16T16:25
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at 2019-11-18T19:11
at 2019-11-18T19:11
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at 2019-11-20T16:47
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at 2019-11-29T01:05
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at 2019-12-02T21:17
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at 2019-12-13T07:54
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at 2019-12-14T00:26
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at 2019-12-18T18:37
at 2019-12-18T18:37
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at 2019-12-20T13:37
at 2019-12-20T13:37
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at 2019-12-22T09:44
at 2019-12-22T09:44
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at 2019-12-22T22:39
at 2019-12-22T22:39
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at 2019-12-23T20:51
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at 2019-12-23T23:45
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at 2020-03-16T03:37
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at 2020-03-20T21:39
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at 2020-05-24T15:10
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at 2020-05-28T00:57
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at 2020-05-29T02:17
at 2020-05-29T02:17
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at 2020-06-01T14:25
at 2020-06-01T14:25
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at 2020-06-05T03:20
at 2020-06-05T03:20
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at 2020-06-06T06:47
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at 2020-06-24T23:53
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at 2020-06-29T11:53
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at 2020-07-01T01:42
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at 2020-07-01T14:21
at 2020-07-01T14:21
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at 2020-07-06T01:07
at 2020-07-06T01:07
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at 2020-07-08T00:27
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at 2020-07-11T21:47
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at 2020-07-15T15:14
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at 2020-07-17T17:03
at 2020-07-17T17:03
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at 2020-07-18T03:19
at 2020-07-18T03:19
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at 2020-07-22T21:15
at 2020-07-22T21:15
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at 2020-07-23T18:31
at 2020-07-23T18:31
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at 2020-07-28T12:12
at 2020-07-28T12:12
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at 2020-09-14T15:46
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at 2020-09-16T10:08
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at 2020-09-19T20:20
at 2020-09-19T20:20
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at 2020-09-21T08:33
at 2020-09-21T08:33
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at 2020-09-22T03:50
at 2020-09-22T03:50
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at 2020-09-23T10:53
at 2020-09-23T10:53
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at 2020-09-23T20:19
at 2020-09-23T20:19
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at 2020-09-28T19:53
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at 2020-10-02T11:32
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at 2020-10-03T14:06
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at 2020-10-06T20:03
at 2020-10-06T20:03
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